Education:

1973-1978:  M.D. Medical Sciences. University of Barcelona, Medical School.

1978-1983: Ph.D. University of Barcelona. Thesis: "Role of platelets in Experimental Atherosclerosis”

1983-1988: Specialist in Hematology and Hemotherapy, University of Barcelona, Medical School.

Professional Experience:

1970-1971: Pharmacology Technician, Almirall Laboratories, Barcelona

1970-1979: Research Assistant in Pharmacology, Department of Pharmacology, High Council for Research (CSIC) Barcelona

1979-1981: Medical Advisor in Pharmacology, Syntex Co, Palo Alto, Ca and Latino, Barcelona

1981-1983: Assistant Physician Department of Hemotherapy and Hemostasis. Hospital Clinic Barcelona

1984-1991 Faculty Member, Hematologist, Department of Hemotherapy and Hemostasis. Hospital Clinic Barcelona

2001-2002: Associate Professor, Transfusion Medicine, Department of Laboratory Medicine and Pathology. University of Minnesota

1992-2006: Head of Section of Hemostasis, Department of Hemotherapy and Hemostasis. Hospital Clinic Barcelona

2007-2011: Head of Department of Hemotherapy and Hemostasis. Hospital Clinic Barcelona

1992 -Present Associate Professor Hematology, University of Barcelona Medical School

2003- Present. Senior Consultant Physician Department of Hemotherapy and Hemostasis, Hospital Clinic, Barcelona

Healthcare experience

Solid background in Experimental and Clinical Pharmacology,  presently focused on Medical Sciences and more specifically on multidisciplinary implications of the Hematology with Hemostasis, Coagulation, Thrombosis, Oncology and Cardiovascular Risk. Specific areas of my expertise include:

Diagnosis and Treatment of Disorders of Hemostasis and Coagulation,

Platelet Function and Platelet Receptor Physiology

Management of Congenital bleeding disorders, Treatment Hemophilia

Hemotherapy, Blood Bank and Transfusion: safety, risks and alternatives to blood transfusion

Interaction of blood with vascular and artificial materials

Antiplatelet therapy: Effectiveness, Resistance, Side-effects, Management of patients under dual therapy

Thrombophilia: Diagnosis, Prevention and Treatment with classic and new anticoagulants

Research Lines:

Characterization of endothelial dysfunction as a common factor in the development of complications associated with multiple diseases. A physiological, biochemical and proteomic approach

Proteomic study for determining the changes in the vascular system and in the different blood cells in thrombotic and bleeding disorders.

Evaluation of the physiological and pathological implications of circulating and/or intraplatelet tissue factor in atherothrombosis.

Study of the mechanisms involved in the development of bleeding and thrombotic disorders

Evaluation of the participation of serotoninergic and purinergic mechanisms in platelet function. Study of the antithrombotic potential of pharmacological inhibitors.

Role of the phenotype/genotype of fibrinolysis and its repercussions upon global or specific functional tests in hemorrhagic and thrombotic pathology.

Evaluation of the potential of clotting factor concentrates to reverse the anticoagulant action of the new oral antithrombotic agents