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This work was supported by the official Spanish Institutions for funding scientific biomedical research, CIBER Fisiopatologia de la Obesidad y Nutricion (CIBERobn) and Instituto de Salud Carlos III (ISCIII), through the Fondo de Investigacion para la Salud (FIS), which is co-funded by the European Regional Development Fund (four coordinated FIS projects leaded by J.S.-S. and J.Vi., including the following projects: PI13/00462, PI13/01090, PI13/02184, PI14/00853, PI14/00728, PI14/01919, PI16/00501, PI16/00381, PI16/01522, PI17/00525, PI17/00532, PI17/00215, PI17/00926 and the Especial Action Project entitled: Implementacion y evaluacion de una intervencion intensiva sobre la actividad fisica Cohorte PREDIMED-Plus [J.S.-S.]; the European Research Council (Advanced Research Grant 2013-2018; grant number 340918); the Recercaixa (grant number 2013ACUP00194) [J.S.-S.]; the SEMERGEN grant; International Nut & Dried Fruit Council -FESNAD (Long-term effects of an energy-restricted Mediterranean diet on mortality and cardiovascular disease 2014 -2015, No. 201302) [Miguel A. Martinez-Gonzalez]; the AstraZeneca Young Investigators Award in Category of Obesity and T2D 2017 [D.R.]; Juan de la Cierva-formacion research grant (FJCI-2015-24058) of the Spanish Ministry of Economy, Industry and Competitiveness [J.K.]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Lifestyle factors and visceral adipose tissue: Results from the PREDIMED-PLUS study

Publicat a:Plos One. 14 (1): e0210726- - 2019-01-25 14(1), DOI: 10.1371/journal.pone.0210726

Autors: Galmes-Panades, Aina M; Konieczna, Jadwiga; Abete, Itziar; Colom, Antoni; Rosique-Esteban, Nuria; Angeles Zulet, Maria; Vazquez, Zenaida; Estruch, Ramon; Vidal, Josep; Toledo, Estefania; Babio, Nancy; Fiol, Miguel; Casas, Rosa; Vera, Josep; Buil-Cosiales, Pilar; Antonio de Paz, Jose; Goday, Albert; Salas-Salvado, Jordi; Alfredo Martinez, J; Romaguera, Dora; Monino, Manuel; Morey, Margarita; Pereira, Veronica; Angeles Martin, Maria; Yanez, Aina; Llobera, Joan; Ripoll, Joana; Prieto, Rafael; Grases, Felix; Costa, Antonia; Fernandez-Palomeque, Carlos; Fortuny, Elena; Noris, Marta; Munuera, Susana; Tomas, Francisco; Fiol, Francisca; Jover, Antoni; Ma Janer, Juana; Vallespir, Catalina; Mattei, Isabel; Feuerbach, Natalia; del Mar Sureda, Maria; Vega, Silvia; Quintana, Lourdes; Fiol, Aina; Amador, Miriam; Gonzalez, Susana; Coll, Joan; Moya, Ana; Dolores Sanmartin, Teresa Pique y Maria; Pena, Cristina; Cantero, Irene; Cristobo, Carmen; Ibero-Baraibar, Idoia; Agreda Martinez, Javier; Lezaun Burgui, Ma Dolores; Goni Ruiz, Nuria; Bartolome Resano, Rafael; Cano Caceres, Eugenia; Elcarte Lopez, Teresa; Echarte Osacain, Elena; Perez Sanz, Beatriz; Blanco Platero, Itziar; Andueza Azcarate, Simón Antonio; Gimeno Aznar, Alvaro; Ursua Sesma, Eugenia; Ojeda Bilbao, Benito; Martinez Jarauta, Javier; Ugalde Sarasa, Lourdes; Ripodas Echarte, Blanca; Gueto Rubio, Ma Victoria; Diaz-Lopez, Andres; Pedret Llaberia, Roser; Gonzalez, Rosi; Sagarra Alamo, Ramon; Paris Palleja, Fransec; Balsells, Josep; Roca, Josep M; Basora Gallisa, Teresa; Vizcaino, Jesus; Llobet Alpizarte, Pilar; Anguera Perpina, Carmen; Llaurado Vernet, Montse; Caballerom, Carmen; Garcia Barco, Maite; Moran Martinez, Maria Dolores; Garcia Rossello, Josep; Del Pozo, Albert; Poblet Calaf, Carmina; Arcelin Zabal, Pierre; Floresvi, Xavier; Ciutat Benet, Marta; Palau Galindo, Antonio; Cabre Vila, Josep J; Dolz Andres, Fernando; Soler, Marc; Gracia Vidal, Mayte; Maritxell Ricard, J Vilalta Juan Boj Casajuana; Saiz, F; Isach, Anna; Marin Martinez, M Sanchez; Granado Font, Esther; Lucena Luque, Carmen; Bullo, Monica; Becerra-Tomas, Nerea; Mestres, Gloria; Basora, Josep; Mena-Sanchez, Guilermo; Barrubes Pinol, Laura; Gil Segura, Marta; Papandreou, Christopher; Chig, Samira; Abellan Cano, I; Ruiz Garcia, Veronica; Salas-Huetos, Albert; Paz, Indira; Sanchez Niembro, Laura; Hernandez, Pablo; Camacho-Barcia, Lucia; Garcia-Gavilan, Jesus; Mestre Reina, Carla; Martinez de la Victoria, Emilio Ortega; Vinagre Torres, Irene; Viaplana Masclans, Judit; Pla Puig, Jose Ignacio; Tania-Marisa; Freitas-Simoes; Domenech, M; Sierra, C; Camafort, M; Fontana, Gabriel; Castro, S; Sadurni, M; Vinas, C; Villanueva, P; Soriano, R; de la Poza, M; Cots, J M; Llovet, J M; Carbonell, C; Garcia, Y; Altirriba, J; Aragunde, V; Fernandez Villa, Tania; de Abajo Olea, Serafín; Escobar Fernandez, Miguel; Fernandez Vazquez, Jose Pedro; Lopez de la Iglesia, Jaime; Lopez Gil, Juan Ignacio; Carriedo Ule, Elena; Rodriguez Bul, Manuel; Adlbi Sibai, Abdurrahman; Garcia Hernandez, Alberto

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Resum

Visceral adipose tissue (VAT) is a strong predictor of cardiometabolic health, and lifestyle factors may have a positive influence on VAT depot. This study aimed to assess the cross-sectional associations between baseline levels of physical activity (PA), sedentary behaviours (SB) and adherence to the Mediterranean diet (MedDiet) with VAT depot in older individuals with overweight/obesity and metabolic syndrome.Baseline data of the PREDIMED-Plus study including a sample of 1,231 Caucasian men and women aged 55-75 years were used. Levels of leisure-time PA (total, light, and moderate-to-vigorous, in METs·min/day) and SB (total and TV-viewing, in h/day) were evaluated using validated questionnaires. Adherence to the MedDiet was evaluated using a 17-item energy-restricted MedDiet (erMedDiet) screener. The chair-stand test was used to estimate the muscle strength. VAT depot was assessed with DXA-CoreScan. Multivariable adjusted linear regression models were used to evaluate the association between lifestyle factors and VAT. For the statistics we had used multiadjusted linear regression models.Total leisure-time PA (100 METs·min/day: β -24.3g, -36.7;-11.9g), moderate-to-vigorous PA (β -27.8g, 95% CI -40.8;-14.8g), chair-stand test (repeat: β -11.5g, 95% CI -20.1;-2.93g) were inversely associated, and total SB (h/day: β 38.2g, 95% CI 14.7;61.7) positively associated with VAT. Light PA, TV-viewing time and adherence to an erMedDiet were not significantly associated with VAT.In older adults with overweigh/obesity and metabolic syndrome, greater PA, muscle strength, and lower total SB were associated with less VAT depot. In this study, adherence to an erMedDiet was not associated with lower VAT.

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