{rfName}
Co

Indexed in

License and use

Altmetrics

Analysis of institutional authors

Brugaletta SCorresponding AuthorOrtega-Paz LAuthorSerra AAuthorSabate MAuthor
Share
Publications
>
Article

Correlates of non-target vessel-related adverse events in patients with ST-segment elevation myocardial infarction: insights from five-year follow-up of the EXAMINATION trial.

Publicated to:Eurointervention. 13 (16): 1939-1945 - 2018-03-01 13(16), DOI: 10.4244/eij-d-17-00608

Authors: Spitaleri, Giosafat; Moscarella, Elisabetta; Brugaletta, Salvatore; Pernigotti, Alberto; Ortega-Paz, Luis; Gomez-Lara, Josep; Cequier, Angel; Iniguez, Andres; Serra, Antonio; Jimenez-Quevedo, Pilar; Mainar, Vicente; Campo, Gianluca; Tespili, Maurizio; den Heijer, Peter; Bethencourt, Armando; Vazquez, Nicolas; Valgimigli, Marco; Serruys, Patrick W; Sabate, Manel

Affiliations

Amphia Ziekenhuis, Dept Cardiol, Breda, Netherlands      Amphia Hospital - Author
Azienda Osped Univ Ferrara, Cardiovasc Inst, Cona, FE, Italy      University of Ferrara    Arcispedale Sant'Anna - Author
Hosp Clin Barcelona, IDIBAPS, Cardiovasc Clin Inst, Carrer Villarroel 170, E-08036 Barcelona, Spain.      University of Barcelona    Hospital Clinic de Barcelona    IDIBAPS - Author
Hosp do Meixoeiro, Dept Cardiol, Vigo, Spain      Complexo Hospitalario Universitario de Vigo       - Author
Hosp Gen Alicante, Dept Cardiol, Alicante, Spain      General University Hospital of Alicante - Author
Hosp Juan Canalejo, Dept Cardiol, La Coruna, Spain      Complejo Hospitalario Universitario A Coruna - Author
Hosp Son Espases, Dept Cardiol, Palma De Mallorca, Spain      Hospital Universitario Son Espases - Author
Imperial Coll London, Int Ctr Circulatory Hlth, London, England      Imperial College London - Author
Maria Cecilia Hosp, ES Hlth Sci Fdn, GVM Care & Res, Cotignola, Italy      Maria Cecilia Hospital       - Author
Univ Hosp Bellvitge, Dept Cardiol, Barcelona, Spain      Bellvitge University Hospital    Catalan Health Institute    University of Barcelona - Author
Univ Hosp Bern, Inselspital, Bern, Switzerland      University Hospital of Bern    University of Bern - Author
Univ Hosp Bolognini Seriate, Dept Cardiol, Bergamo, Italy - Author
Univ Hosp Clin, IDIBAPS, Cardiovasc Clin Inst, Barcelona, Spain      Hospital Clinic de Barcelona    University of Barcelona    IDIBAPS - Author
Univ Hosp San Carlos, Dept Cardiol, Madrid, Spain      Hospital Clinico San Carlos - Author
Univ Hosp St Pau, Dept Cardiol, Barcelona, Spain - Author
See more

Abstract

The aim of this substudy was to determine the five-year correlates of non-TV-related adverse events (AE) in STEMI patients included in the EXAMINATION trial.The EXAMINATION trial randomised 1,498 STEMI patients to bare metal or everolimus-eluting stent implantation. In this substudy, patients were analysed according to non-TV-related AE, defined as the composite of either non-TV revascularisation (non-TVR) or non-TV-related myocardial infarction (MI). At five-year follow-up, 125 patients (8.3%) exhibited 136 non-TV-related AE (124 [8.3%] non-TVR, 12 [0.8%] non-TV-related MI), accounting for 47.1% of 289 non-fatal cardiac events overall. These patients had a higher incidence of diabetes mellitus (p<0.001), arterial hypertension (p=0.032), previous MI (p=0.073), multivessel disease (p<0.001), and incomplete revascularisation (p=0.049), and a lower rate of ST-segment resolution >70% (p=0.042) as compared to the rest. At Cox analysis, previous MI (HR 1.872, 95% CI: 1.004-3.489; p=0.048), incomplete revascularisation (HR 1.746, 95% CI: 1.029-2.963; p=0.039) and diabetes (HR 1.942, 95% CI: 1.292-2.919; p=0.001) were independent correlates of non-TV-related AE.In STEMI patients undergoing primary percutaneous coronary intervention, previous MI, incomplete revascularisation and diabetes resulted in being independent correlates of five-year non-TV-related AE.

Keywords
atherosclerosisbare-metal stentclinical-outcomescomplete revascularizationculprit lesiondiabetic-patientsdrug-eluting stentmultiple vessel diseaseprogressionrandomized controlled-trialsirolimus-eluting stentst-elevation myocardial infarction (stemi)AgedBare metal stentComorbidityCoronary-artery-diseaseDiabetes mellitusDrug-eluting stentDrug-eluting stentsFemaleHumansIncidenceMaleMetalsMiddle agedMultiple vessel diseasePercutaneous coronary interventionProsthesis designRecurrenceRisk factorsSt elevation myocardial infarctionSt-elevation myocardial infarction (stemi)StentsTime factorsTreatment outcome

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Eurointervention due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2018, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Medicine (Miscellaneous). Notably, the journal is positioned above the 90th percentile.

From a relative perspective, and based on the normalized impact indicator calculated from the Field Citation Ratio (FCR) of the Dimensions source, it yields a value of: 2.37, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: Dimensions May 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-05-10, the following number of citations:

  • WoS: 9
  • Scopus: 10
  • Europe PMC: 5
  • OpenCitations: 9
Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-10:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 59.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 59 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 16.55.
  • The number of mentions on the social network X (formerly Twitter): 33 (Altmetric).
Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: France; Italy; Netherlands; Switzerland; United Kingdom.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Spitaleri G) and Last Author (Sabaté Tenas, Manel).

the author responsible for correspondence tasks has been Brugaletta, Salvatore.