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This project was unfunded. However, Nilam Soni's time is partially funded by the Department of Veterans Affairs, Quality Enhancement Research Initiative (QUERI) Partnered Evaluation Initiative Grant (HX002263-01A1). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Department of Veterans Affairs, nor the United States Government.

Analysis of institutional authors

Torres Marti, AntoniAuthorMartinez Chamorro, EstebanAuthorGonzalez Franquesa, AlbaAuthorBrito, VeronicaAuthorSibila OAuthorCilloniz, CAuthorGlimpAuthor

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Article

Burden and risk factors for Pseudomonas aeruginosa community-acquired pneumonia: a multinational point prevalence study of hospitalised patients

Publicated to:European Respiratory Journal. 52 (2): 1701190- - 2018-08-01 52(2), DOI: 10.1183/13993003.01190-2017

Authors: Restrepo, Marcos, I; Babu, Bettina L; Reyes, Luis F; Chalmers, James D; Soni, Nilam J; Sibila, Oriol; Faverio, Paola; Cilloniz, Catia; Rodriguez-Cintron, William; Aliberti, Stefano

Affiliations

Clin Univ La Sabana, Dept Crit Care Med, Chia, Colombia - Author
Clin Univ La Sabana, Dept Crit Care Med, Chia, Colombia      Universidad de La Sabana - Author
Fdn IRCCS Ca Granda Osped Maggiore Policlin, Adult Cyst Fibrosis Ctr, Milan, Italy - Author
Fdn IRCCS Ca Granda Osped Maggiore Policlin, Adult Cyst Fibrosis Ctr, Milan, Italy      IRCCS Ca Granda Ospedale Maggiore Policlinico - Author
South Texas Vet Hlth Care Syst, Div Pulm Dis & Crit Care Med, San Antonio, TX USA - Author
South Texas Vet Hlth Care Syst, Div Pulm Dis & Crit Care Med, San Antonio, TX USA      Audie L. Murphy Memorial Veterans Hospital    US Department of Veteran Affairs - Author
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Dept Med, Serv Pneumol, Barcelona, Spain - Author
Univ Autonoma Barcelona, Hosp Santa Creu & St Pau, Dept Med, Serv Pneumol, Barcelona, Spain      Autonomous University of Barcelona    Hospital of Santa Creu i Sant Pau - Author
Univ Barcelona, CIBER, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Dept Pneumol,Inst Clin Torax,Hosp Clin Barcelona, Barcelona, Spain - Author
Univ Barcelona, CIBER, Inst Invest Biomed August Pi & Sunyer IDIBAPS, Dept Pneumol,Inst Clin Torax,Hosp Clin Barcelona, Barcelona, Spain      IDIBAPS    University of Barcelona    Hospital Clinic de Barcelona       - Author
Univ Dundee, Sch Med, Dundee, Scotland - Author
Univ Dundee, Sch Med, Dundee, Scotland      University of Dundee - Author
Univ La Sabana, Dept Microbiol, Chia, Colombia - Author
Univ la Sabana, Dept Microbiol, Chia, Colombia      Universidad de La Sabana - Author
Univ Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy - Author
Univ Milan, Dept Pathophysiol & Transplantat, Cardiothorac Unit, Milan, Italy      University of Milan - Author
Univ Milano Bicocca, Resp Unit, San Gerardo Hosp, ASST Monza,Cardiothorac Vasc Dept, Monza, Italy - Author
Univ Milano Bicocca, Resp Unit, San Gerardo Hosp, ASST Monza,Cardiothorac Vasc Dept, Monza, Italy      San Gerardo Hospital    University of Milano-Bicocca - Author
Univ Texas Hlth San Antonio, Div Pulm Dis & Crit Care Med, San Antonio, TX USA - Author
Univ Texas Hlth San Antonio, Div Pulm Dis & Crit Care Med, San Antonio, TX USA      University of Texas System    University of Texas Health San Antonio - Author
VA Caribbean Healthcare Syst, Pulm Crit Care Med, San Juan, PR USA - Author
      South Texas Vet Hlth Care Syst ALMD, 7400 Merton Minter Blvd, San Antonio, TX 78229 USA. - Author
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Abstract

Pseudomonas aeruginosa is a challenging bacterium to treat due to its intrinsic resistance to the antibiotics used most frequently in patients with community-acquired pneumonia (CAP). Data about the global burden and risk factors associated with P. aeruginosa-CAP are limited. We assessed the multinational burden and specific risk factors associated with P. aeruginosa-CAP.We enrolled 3193 patients in 54 countries with confirmed diagnosis of CAP who underwent microbiological testing at admission. Prevalence was calculated according to the identification of P. aeruginosa Logistic regression analysis was used to identify risk factors for antibiotic-susceptible and antibiotic-resistant P. aeruginosa-CAP.The prevalence of P. aeruginosa and antibiotic-resistant P. aeruginosa-CAP was 4.2% and 2.0%, respectively. The rate of P. aeruginosa CAP in patients with prior infection/colonisation due to P. aeruginosa and at least one of the three independently associated chronic lung diseases (i.e. tracheostomy, bronchiectasis and/or very severe chronic obstructive pulmonary disease) was 67%. In contrast, the rate of P. aeruginosa-CAP was 2% in patients without prior P. aeruginosa infection/colonisation and none of the selected chronic lung diseases.The multinational prevalence of P. aeruginosa-CAP is low. The risk factors identified in this study may guide healthcare professionals in deciding empirical antibiotic coverage for CAP patients.The content of this work is not subject to copyright. Design and branding are copyright ©ERS 2018.

Keywords

antibiotic-therapyenterobacteriaceaeepidemiologygram-negative bacteriaguidelinesinfectious-diseases-societymanagementmultidrug-resistant pathogensoutcomesAgedAged, 80 and overBronchiectasisCare-associated pneumoniaCommunity-acquired infectionsCommunity-acquired pneumoniaCross infectionCross-sectional studiesDrug resistance, bacterialFemaleHumansInternationalityLogistic modelsMaleMiddle agedPneumònia adquirida a la comunitatPneumonia, bacterialPrevalencePseudomonasPseudomonas aeruginosaPulmonary disease, chronic obstructiveRisk factorsTracheostomy

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal European Respiratory Journal due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2018, it was in position 4/63, thus managing to position itself as a Q1 (Primer Cuartil), in the category Respiratory System. Notably, the journal is positioned above the 90th percentile.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 5.84. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Field Citation Ratio (FCR) from Dimensions: 33.1 (source consulted: Dimensions Jun 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-06-13, the following number of citations:

  • WoS: 135
  • Europe PMC: 59
  • OpenCitations: 137

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-13:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 303.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 303 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 38.85.
  • The number of mentions on the social network X (formerly Twitter): 17 (Altmetric).
  • The number of mentions in news outlets: 3 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Colombia; Italy; Puerto Rico; United Kingdom; United States of America.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (Ceccato, Adrian).