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Analysis of institutional authors

Codina JAuthorGarcía-Algar OAuthor

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May 30, 2022
Publications
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Review

Detection of the Synthetic Cannabinoids AB-CHMINACA, ADB-CHMINACA, MDMB-CHMICA, and 5F-MDMB-PINACA in Biological Matrices: A Systematic Review

Publicated to: Biology. 11 (5): 796- - 2022-05-01 11(5), DOI: 10.3390/biology11050796

Authors:

Navarro-Tapia, E; Codina, J; Villanueva-Blasco, VJ; García-Algar, O; Andreu-Fernández, V
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Affiliations

Department of Neonatology, Hospital Clínic-Maternitat, ICGON, BCNatal, 08028 Barcelona, Spain. - Author
Faculty of Health Sciences, Valencian International University (VIU), 46002 Valencia, Spain. - Author
Grup de Recerca Infancia i Entorn (GRIE), Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain. - Author
Hosp Clin Maternitat, Dept Neonatol, BCNatal, ICGON, Barcelona 08028, Spain - Author
Inst Invest Biomed August Pi & Sunyer IDIBAPS, Grp Recerca Infancia & Entorn GRIE, Barcelona 08036, Spain - Author
Valencian Int Univ VIU, Fac Hlth Sci, Valencia 46002, Spain - Author
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Abstract

New synthetic cannabinoids (SCs) are emerging rapidly and continuously. Biological matrices are key for their precise detection to link toxicity and symptoms to each compound and concentration and ascertain consumption trends. The objective of this study was to determine the best human biological matrices to detect the risk-assessed compounds provided by The European Monitoring Centre for Drugs and Drug Addiction: AB-CHMINACA, ADB-CHMNACA, MDMB-CHMICA, and 5F-MDMB-PINACA. We carried out a systematic review covering 2015 up to the present date, including original articles assessing detection in antemortem human biological matrices with detailed validation information of the technique. In oral fluid and blood, SC parent compounds were found in oral fluid and blood at low concentrations and usually with other substances; thus, the correlation between SCs concentrations and severity of symptoms could rarely be established. When hair is used as the biological matrix, there are difficulties in excluding passive contamination when evaluating chronic consumption. Detection of metabolites in urine is complex because it requires prior identification studies. LC-MS/MS assays were the most widely used approaches for the selective identification of SCs, although the lack of standard references and the need for revalidation with the continuous emergence of new SCs are limiting factors of this technique. A potential solution is high-resolution mass spectrometry screening, which allows for non-targeted detection and retrospective data interrogation.
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Keywords

5f-adb5f-mdmb-pinacaab-chminacaabuseadb-chmnacabehaviorconsumptiondetectiondrugsfatal intoxicationfuturehairhrmshuman matrixmdmb-chmicametabolitestoxicologyurine5f-adb5f-mdmb-pinacaAb-chminacaAdb-chmnacaDetectionHrmsHuman matrixMdmb-chmicaPsychoactive substancesSynthetic cannabinoidsToxicology

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Biology due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2022, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Agricultural and Biological Sciences (Miscellaneous).

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.18. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 13, 2025)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Weighted Average of Normalized Impact by the Scopus agency: 1.92 (source consulted: FECYT Mar 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-12-31, the following number of citations:

  • WoS: 10
  • Scopus: 10
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-12-31:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 27.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 27 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network X (formerly Twitter): 1 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Navarro-Tapia E) and Last Author (Andreu-Fernández V).

the author responsible for correspondence tasks has been Andreu-Fernández V.

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Awards linked to the item

This research was funded by Red de Salud Materno-Infantil y del Desarrollo (SAMID) and Instituto de Salud Carlos III (ISCIII) (RD12/0026/0003 and RD16/0022/0002), (PI16/00566 and PI19/01853), co-funded by the European Union and Primary Care Interventions to Prevent Maternal and Child Chronic Diseases of Perinatal and Developmental Origin (RICORS), RD21/0012/0017, Instituto de Salud Carlos III, Madrid, Spain.
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