Diagnostic Accuracy and Detection Rate of Glaucoma Screening with Optic Disk Photos, Optical Coherence Tomography Images, and Telemedicine

January 11, 2023

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Publicated to:Journal Of Clinical Medicine. 11 (1): 216- - 2022-01-01 11(1), DOI: 10.3390/jcm11010216

Authors: Anton, A; Nolivos, K; Pazos, M; Fatti, G; Ayala, ME; Martinez-Prats, E; Peral, O; Poposki, V; Tsiroukis, E; Morilla-Grasa, A; Comas, M; Castells, X

Affiliations

Cap Barceloneta, Barcelona 08005, Spain - Author

Cap Villa Olimp, Barcelona 08005, Spain - Author

Hosp Clin Barcelona, Inst Clin Oftalmol ICOF, Inst Invest Med, Barcelona 08036, Spain - Author

Inst Catala Retina ICR, Res Dept, Barcelona 08017, Spain - Author

Inst Mar Invest Med IMIM, Dept Med, Barcelona 08005, Spain - Author

Inst Salud Carlos III, Hlth Serv Res Chron Patients Network REDISSEC, Madrid 28029, Spain - Author

Parc De Salut Mar, Ophthalmol Serv, Barcelona 08005, Spain - Author

Parc Salut Mar, Epidmiol & Evaluat Dept, Barcelona 08005, Spain - Author

Univ Int Catalunya, Med Sch, Barcelona 08017, Spain - Author

Abstract

Purpose: The aim of this study was to evaluate the diagnostic accuracy of optical coherence tomography (OCT) and retinography in the detection of glaucoma through a telemedicine program. Methods: A population-based sample of 4113 persons was randomly selected. The screening examination included a fundus photograph and OCT images. Images were evaluated on a deferred basis. All participants were then invited to a complete glaucoma examination, including gonioscopy, visual field, and dilated fundus examination. The detection rate, sensitivity, specificity, and positive and negative predictive values were calculated. Results: We screened 1006 persons. Of these, 201 (19.9%) were classified as glaucoma suspects; 20.4% were identified only by retinographs, 11.9% only by OCT images, and 46.3% by both. On ophthalmic examination at the hospital (n = 481), confirmed glaucoma was found in 58 (12.1%), probable glaucoma in 76 (15.8%), and ocular hypertension in 10 (2.1%), and no evidence of glaucoma was found in 337 (70.0%). The detection rate for confirmed or probable glaucoma was 9.2%. Sensitivity ranged from 69.4% to 86.2% and specificity from 82.1% to 97.4%, depending on the definition applied. Conclusions: The combination of OCT images and fundus photographs yielded a detection rate of 9.2% in a population-based screening program with moderate sensitivity, high specificity, and predictive values of 84-96%.

Keywords

glaucomaoptical coherence tomographyretinographyscreeningCost-effectivenessGlaucomaImaging devicesNerve-fiber layerOpen-angle glaucomaOptical coherence tomographyPopulationPrevalenceRetinographyScreeningTelemedicineTests

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Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Journal Of Clinical Medicine due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2022, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Medicine (Miscellaneous).

From a relative perspective, and based on the normalized impact indicator calculated from the Field Citation Ratio (FCR) of the Dimensions source, it yields a value of: 5.71, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-03, the following number of citations:

WoS: 4

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