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Impact on the Sustainable Development Goals (SDGs)

Analysis of institutional authors

Di Trani, Claudia AugustaAuthor

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February 13, 2024
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Editorial Material
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Interleukin-12 Message in a Bottle

Publicated to: Clinical Cancer Research. 26 (23): 6080-6082 - 2020-12-01 26(23), DOI: 10.1158/1078-0432.CCR-20-3250

Authors:

Cirella, A; Berraondo, P; Di Trani, CA; Melero, I; Cirella, A; Berraondo, P; Di Trani, CA; Melero, I; Berraondo, P; Melero, I; Melero, I
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Affiliations

Cima Univ Navarra, Program Immunol & Immunotherapy, Pamplona, Spain - Author
Clin Univ Navarra, Dept Immunol & Immunotherapy, Pamplona, Spain - Author
Ctr Invest Biomed Red Canc CIBERONC, Madrid, Spain - Author
Navarra Inst Hlth Res IdiSNA, Pamplona, Spain - Author
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Abstract

IL12 is a very potent cancer immunotherapy agent, but is difficult to harness safely if given systemically. Local gene transfer aims to confine the effects of IL12 to malignant tissues, thus avoiding toxicity. Lipid-nanoparticle mRNA achieves IL12 expression and efficacy in mouse models, opening the way to an ongoing trial.
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Keywords

Good health and well-being

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal CLINICAL CANCER RESEARCH due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2020, it was in position 18/242, thus managing to position itself as a Q1 (Primer Cuartil), in the category Oncology. Notably, the journal is positioned above the 90th percentile.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-02:

  • Open Alex: 10
  • WoS: 5
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-02:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 12.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 12 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Continuing with the social impact of the work, it is important to emphasize that, due to its content, it can be assigned to the area of interest of ODS 3 - Good Health And Well-being, with a probability of 83% according to the mBERT algorithm developed by Aurora University.
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Awards linked to the item

This work was supported by European Union's Horizon 2020 research and innovation programme under the Marie Skoodowska-Curie grant agreement no 765394, Spanish Ministry of Economy and Competitiveness (MINECO SAF 201783267-C2-1R [AEI/FEDER, UE]), Cancer Research Institute (CRI), Asociacion Espanola Contra el Cancer (AECC) Foundation under Grant GCB15152947MELE, H2020 PROCROP project under Grant 635122, Instituto de Salud Carlos III (PI19/01128) cofinanced by Fondos Feder and Joint Translational Call for Proposals 2015 (JTC 2015) TRANSCAN-2 (code: TRS-2016-00000371).
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