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Ausania, FabioAuthorGonzalez-Abos, CarolinaCorresponding AuthorRios, JoseAuthor

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September 29, 2024
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Conversion to open surgery in obese patients undergoing minimally invasive distal pancreatectomy: results from a multicenter analysis

Publicated to:Hpb. 26 (9): 1172-1179 - 2024-09-01 26(9), DOI: 10.1016/j.hpb.2024.05.016

Authors: Ausania, Fabio; Gonzalez-Abos, Carolina; Landi, Filippo; Martinie, John B; Vrochides, Dionisios; Walsh, Matthew; Hossain, Shanaz M; White, Steven; Prabakaran, Viswakumar; Melstrom, Laleh G; Fong, Yuman; Butturini, Giovanni; Bignotto, Laura; Valle, Valentina; Bing, Yuntao; Xiu, Dianrong; Di Franco, Gregorio; Sanchez-Bueno, Francisco; de'Angelis, Nicola; Laurent, Alexis; Giuliani, Giuseppe; Pernazza, Graziano; Esposito, Alessandro; Salvia, Roberto; Bazzocchi, Francesca; Esposito, Ludovica; Pietrabissa, Andrea; Pugliese, Luigi; Memeo, Riccardo; Uyama, Ichiro; Uchida, Yuichiro; Rios, Jose; Coratti, Andrea; Morelli, Luca; Giulianotti, Pier C

Affiliations

Acquaviva Fonti Hosp, Dept Surg, Bari, Italy - Author
Beijing Third Hosp, Dept Gen Surg, Beijing, Peoples R China - Author
Carolinas Med Ctr, Dept Surg, Div HPB Surg, Charlotte, NC USA - Author
City Hope Med Ctr, Div Surg Oncol, Gastrointestinal Dis Team, Duarte, CA USA - Author
Cleveland Clin, Digest Dis & Surg Inst, HPB Surg Dept, Cleveland, OH USA - Author
Fujita Hlth Univ, Sch Med, Dept Surg, Toyoake, Japan - Author
Henri Mondor Hosp, AP HP, Dept Digest HBP Surg & Liver Transplantat, Creteil, France - Author
Hosp Clin Barcelona, Inst Invest Biomed August Pi i Sunyer IDIBAPS, Dept HBP Surg & Transplantat, Gen & Digest Surg, Barcelona, Spain - Author
IRCCS Casa Sollievo Soferenza Hosp, Dept HBP Surg, Foggia, Italy - Author
Misericordia Hosp, Div Gen & Minimally Invas Surg, Grosseto, Italy - Author
NHS, Freeman Hosp, Newcastle Upon Tyne, England - Author
P Pederzoli Hosp, Dept HBP Surg, Peschiera Del Garda, Italy - Author
Policlin GB Rossi Hosp, HBP Surg Dept, Verona, Italy - Author
Policlin S Matteo Hosp, Dept HBP Surg, Pavia, Italy - Author
San Giovanni Hosp, Gen & Robot Surg Dept, Rome, Italy - Author
Univ Autonoma Barcelona UAB, Hosp Clin, Fac Med, Dept Clin Pharmacol, Barcelona, Spain - Author
Univ Autonoma Barcelona UAB, Inst Invest Biomed August Pi i Sunyer IDIBAPS, Fac Med, Med Stat Core Facil,Biostat Unit, Barcelona, Spain - Author
Univ Barcelona UB, Fac Med & Ciencies Salut, Barcelona, Spain - Author
Univ Illinois, Dept Surg, Div Gen Minimally Invas & Robot Surg, Chicago, IL USA - Author
Univ Pisa, Gen Surg Dept, Div Translat & New Technol Med & Surg, Pisa, Italy - Author
Virgen Arrixaca Hosp, Dept HBP Surg, Murcia, Spain - Author
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Abstract

Background: Although minimally invasive distal pancreatectomy (MIDP) is considered a standard approach it still presents a non-negligible rate of conversion to open that is mainly related to some difficulty factors, as obesity. The aim of this study is to analyze the preoperative factors associated with conversion in obese patients with MIDP. Methods: In this multicenter study, all obese patients who underwent MIDP at 18 international expert centers were included. The preoperative factors associated with conversion to open surgery were analyzed. Results: Out of 436 patients, 91 (20.9%) underwent conversion to open, presenting higher blood loss, longer operative time and similar rate of major complications. Twenty (22%) patients received emergent conversion. At univariate analysis, the type of approach, radiological invasion of adjacent organs, preoperative enlarged lymphnodes and ASA > III were significantly associated with conversion to open. At multivariate analysis, robotic approach showed a significantly lower conversion rate (14.6 % vs 27.3%, OR = 2.380, p = 0.001). ASA > III (OR = 2.391, p = 0.002) and preoperative enlarged lymphnodes (OR = 3.836, p = 0.003) were also independently associated with conversion. Conclusion: Conversion rate is significantly lower in patients undergoing robotic approach. Radiological enlarged lymphnodes and ASA > III are also associated with conversion to open. Conversion is associated with poorer perioperative outcomes, especially in case of intraoperative hemorrhage.

Keywords

AdultAdverse eventAgedArticleBleedingBlood loss, surgicalChi square distributionChi-square distributionClinical trialComplicationComplicationsConversion to open surgeryDefinitionDistal pancreatectomyEtiologyEuropeFemaleFollow upHospital mortalityHospitalizationHumanHumansInternational study-groupLaparoscopyLaparotomyLength of stayLogistic modelsMajor clinical studyMaleMiddle agedMinimally invasive procedureMortalityMulticenter studyMultivariate analysisObese patientObesityOdds ratioOpen surgeryOperation durationOperative blood lossOperative timePancreatectomyPerioperative periodPostoperative complicationPostoperative complicationsPostoperative hemorrhageProceduresRadiologistRetrospective studiesRetrospective studyRisk factorRisk factorsRobot assisted surgeryRobotic surgical proceduresSplenectomyStatistical modelSuperioSurgeryThyroidectomyTime factorTime factorsTreatment outcomeUnivariate analysisWound infection

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Hpb due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position 78/312, thus managing to position itself as a Q1 (Primer Cuartil), in the category Surgery.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-08-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 6.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 15 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.85.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: China; France; Italy; Japan; United Kingdom; United States of America.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Ausania, Fabio) .

the author responsible for correspondence tasks has been González Abós, Carolina.