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Part of our results has been accepted as an e-Poster to be presented at the 37th annual congress of the European Society of Intensive Care Medicine, to be held in October 2024.

Analysis of institutional authors

Fernandez, SaraAuthorBerrocal, LeireAuthorMiro, Jose MAuthorNicolas, Jose MAuthorMallolas, JosepAuthorCastro, PedroCorresponding AuthorDe La Mora, LorenaAuthor
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Article

Epidemiological changes and outcomes of people living with HIV admitted to the intensive care unit: a 14-year retrospective study

Publicated to:Infection. - 2024-10-11 (), DOI: 10.1007/s15010-024-02402-x

Authors: Martínez E; Foncillas A; Téllez A; Fernández S; Martínez-Nadal G; Rico V; Tomé A; Ugarte A; Rinaudo M; Berrocal L; De Lazzari E; Miró JM; Nicolás JM; Mallolas J; De la Mora L; Castro P

Affiliations

Hosp Clin Barcelona, Emergency Dept, Barcelona, Spain - Author
Hosp Clin Barcelona, Hosp Home, Barcelona, Spain - Author
Hosp Clin Barcelona, Infect Dis Dept, Barcelona, Spain - Author
Hosp Clin Barcelona, Med Intens Care Unit, Barcelona, Spain - Author
Hosp Gen Granollers, Intens Care Unit, Granollers, Spain - Author
Hosp Sant Joan Despi Moises Broggi, Intens Care Unit, Sant Joan Despi, Spain - Author
IDIBAPS, Barcelona, Spain - Author
Inst Salud Carlos III, CIBERINFEC, Madrid, Spain - Author
Univ A Coruna, Emergency Dept, Complejo Hosp, La Coruna, Spain - Author
Univ Barcelona, Barcelona, Spain - Author
Univ Hosp Vic, Intens Care Unit, Vic, Spain - Author
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Abstract

PurposesSince 2016, the World Health Organization has recommended universal antiretroviral therapy (ART) for all people living with Human Immunodeficiency Virus (PLHIV). This recommendation may have influenced the characteristics and outcomes of PLHIV admitted to the Intensive Care Unit (ICU). This study aims to identify changes in the epidemiological and clinical characteristics of PLHIV admitted to the ICU, and their short- and medium-term outcomes before and after the implementation of universal ART (periods 2006-2015 and 2016-2019).MethodsThis retrospective, observational, single-center study included all adult PLHIV admitted to the ICU of a University Hospital in Barcelona from 2006 to 2019.ResultsThe study included 502 admissions involving 428 patients, predominantly men (75%) with a median (P25-P75) age of 47.5 years (39.7-53.9). Ninety-one percent were diagnosed with HIV before admission, with 82% under ART and 60% admitted from the emergency department. In 2016-2019, there were more patients on ART pre-admission, reduced needs for invasive mechanical ventilation (IMV) and fewer in-ICU complications. ICU mortality was also lower (14% vs 7%). Predictors of in-ICU mortality included acquired immunodeficiency syndrome defining event (ADE)-related admissions, ICU complications, higher SOFA scores, IMV and renal replacement therapy (RRT) requirement. ART use during ICU admission was protective. Higher SOFA scores, admission from hospital wards, and more comorbidities predicted one-year mortality.ConclusionsThe in-ICU mortality of critically ill PLHIV has decreased in recent years, likely due to changes in patient characteristics. Pre- and ICU admission features remain the primary predictors of short- and medium-term outcomes.

Keywords
Acquired immunodeficiency syndrome (aidsAcquired immunodeficiency syndrome (aids)AdultsAntiretroviral therapyAntiretroviral therapy (art)Critical careHiv infectionHuman immunodeficiency virus (hiv)Infected patientsIntensive care unit (icu)Life expectancySurvivalTrend

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Infection due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position 14/132, thus managing to position itself as a Q1 (Primer Cuartil), in the category Infectious Diseases. Notably, the journal is positioned above the 90th percentile.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-05-11:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 5.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 2 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 10.5.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (de la Mora Cañizo, Lorena).

the author responsible for correspondence tasks has been Castro Rebollo, Pedro.