{rfName}

Indexed in

License and use

Citations

1

Altmetrics

Grant support

This study was supported by the Instituto de Salud Carlos III PI20/00693/CB16/11/00354, cofunded by the European Union and grant 2021_SGR_01350, SGR21/GENCAT, Spain.

Analysis of institutional authors

Vázquez-Calvo, SaraAuthorSánchez-Somonte, PaulaAuthorGuichard, Jean-BaptisteAuthorGuasch, EduardAuthorPorta-Sanchéz, AndreuAuthorTolosana, Jose MariaAuthorBorras, RogerAuthorArbelo, ElenaAuthorOrtiz-Perez, Jose TAuthorPerea, Rosario JAuthorBrugada, JosepAuthorMont, LluisAuthorRoca-Luque, IvoCorresponding Author

Share

October 22, 2024
Publications
>
Article
No

Personalized voltage maps guided by cardiac magnetic resonance in the era of high-density mapping

Publicated to:Heart Rhythm. 21 (10): 1811-1819 - 2024-10-01 21(10), DOI: 10.1016/j.hrthm.2024.04.074

Authors: Vazquez-Calvo, Sara; Garre, Paz; Ferro, Elisenda; Sanchez-Somonte, Paula; Guichard, Jean-Baptiste; Falzone, Pasquale Valerio; Guasch, Eduard; Porta-Sanchez, Andreu; Tolosana, Jose Maria; Borras, Roger; Arbelo, Elena; Ortiz-Perez, Jose T; Prats, Susana; Perea, Rosario J; Brugada, Josep; Mont, Lluis; Roca-Luque, Ivo

Affiliations

Ctr Invest Biomed Red Enfermedades Cardiovasc CIBE, Madrid, Spain - Author
Inst Invest Biomed August Pi i Sunyer IDIBAPS, Barcelona, Spain - Author
Inst Salud Carlos III, CIBERSAM, Ctr Invest Biomed Red Salud Mental, Madrid, Spain - Author
Univ Barcelona, Hosp Clin, Inst Clin Cardiovasc, Barcelona, Spain - Author

Abstract

Background Voltage mapping could identify the conducting channels potentially responsible for ventricular tachycardia (VT). Standard thresholds (0.5-1.5 mV) were established using bipolar catheters. No thresholds have been analyzed with high-density mapping catheters. In addition, channels identified by cardiac magnetic resonance (CMR) has been proven to be related with VT. Objective The purpose of this study was to analyze the diagnostic yield of a personalized voltage map using CMR to guide the adjustment of voltage thresholds. Methods All consecutive patients with scar-related VT undergoing ablation after CMR (from October 2018 to December 2020) were included. First, personalized CMR-guided voltage thresholds were defined systematically according to the distribution of the scar and channels. Second, to validate these new thresholds, a comparison with standard thresholds (0.5-1.5 mV) was performed. Tissue characteristics of areas identified as deceleration zones (DZs) were recorded for each pair of thresholds. In addition, the relation of VT circuits with voltage channels was analyzed for both maps. Results Thirty-two patients were included [mean age 66.6 +/- 11.2 years; 25 (78.1%) ischemic cardiomyopathy]. Overall, 52 DZs were observed: 44.2% were identified as border zone tissue with standard cutoffs vs 75.0% using personalized voltage thresholds (P = .003). Of the 31 VT isthmuses detected, only 35.5% correlated with a voltage channel with standard thresholds vs 74.2% using adjusted thresholds (P = .005). Adjusted cutoff bipolar voltages that better matched CMR images were 0.51 +/- 0.32 and 1.79 +/- 0.71 mV with high interindividual variability (from 0.14-1.68 to 0.7-3.21 mV). Conclusion Personalized voltage CMR-guided personalized voltage maps enable a better identification of the substrate with a higher correlation with both DZs and VT isthmuses than do conventional voltage maps using fixed thresholds.

Keywords

AgeAgedAmiodaroneArticleBeta adrenergic receptor blocking agentBipolarBody surface potential mappingCardiac magnetic resonanceCardiac patientCardiovascular magnetic resonanceCatheter ablationChannelsCine magnetic resonance imagingClinical articleComparative studyCorrelational studyDeceleration zoneDiagnosisDiagnostic valueDipeptidyl carboxypeptidase inhibitorElectric potentialElectrophysiologic techniques, cardiacElectrophysiology parametersFemaleHeart conduction systemHeart electrophysiologyHeart function testHeart muscle conduction systemHeart ventricle tachycardiaHigh density mappingHigh-density mappinHigh-density mappingHumanHumansIdentificationIschemic cardiomyopathyLate gadolinium enhancement imagingMagnetic resonance imaging, cineMaleMiddle agedNonischemic cardiomyopathyObservational studyPathophysiologyPersonalized medicineProceduresProspective studyRadiofrequency catheter ablationScarSinus rhythmSiteSotalolStandardSubstrateTachycardia, ventricularVentricular tachycardia ablationVentricular-tachycardiaVoltage mappingVoltage thresholds

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Heart Rhythm due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position 37/230, thus managing to position itself as a Q1 (Primer Cuartil), in the category Cardiac & Cardiovascular Systems.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2025-08-02:

  • Scopus: 1

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-08-02:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 12.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 20 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 24.7.
  • The number of mentions on the social network X (formerly Twitter): 37 (Altmetric).

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Vázquez Calvo, Sara) and Last Author (Roca Luque, Ivo).

the author responsible for correspondence tasks has been Roca Luque, Ivo.