{rfName}
Se

Indexed in

Citations

11

Altmetrics

Analysis of institutional authors

Amoretti, SilviaAuthorSerra-Navarro, MariaAuthorTorrent, CarlaAuthorGarriga, MarinaAuthorFares-Otero, Natalia EAuthorSague-Vilavella, MariaAuthorMadero, SantiagoAuthorForte, M FlorenciaAuthorMontejo, LauraAuthorPacchiarotti, IsabellaAuthorGarcia-Rizo, ClementeAuthorMartinez-Aran, AnabelAuthorVieta, EduardCorresponding AuthorVerdolini, NormaAuthor

Share

November 12, 2024
Publications
>
Article
No

Sex matters: Differences in prodromes, clinical and neuropsychological features in individuals with a first episode mania or psychosis

Publicated to: Journal Of Affective Disorders. 369 449-461 - 2025-01-15 369(), DOI: 10.1016/j.jad.2024.10.002

Authors:

Palacios-Garran, Roberto; Amoretti, Silvia; Serra-Navarro, Maria; Torrent, Carla; Garriga, Marina; Fares-Otero, Natalia E; Sague-Vilavella, Maria; Madero, Santiago; Forte, M Florencia; Montejo, Laura; Salgado-Pineda, Pilar; Montoro, Irene; Sanchez-Gistau, Vanessa; Pomarol-Clotet, Edith; Menculini, Giulia; Tortorella, Alfonso; Pacchiarotti, Isabella; Garcia-Rizo, Clemente; Ramos-Quiroga, Josep Antoni; Martinez-Aran, Anabel; Vieta, Eduard; Verdolini, Norma
[+]

Affiliations

CIBERSAM ISCIII, FIDMAG Germanes Hosp Res Fdn, St Boi De Llobregat, Barcelona, Spain - Author
Hosp Univ Vall dHebron, Dept Psychiat, Barcelona, Catalonia, Spain - Author
Mental Hlth Ctr Perugia, Dept Mental Hlth, Local Hlth Unit Umbria 1, Perugia, Italy - Author
Univ Barcelona UB, Dept Med, Fac Med & Ciencies Salut, Barcelona, Spain - Author
Univ Barcelona UB, Hosp Clin Barcelona, Inst Neurociencies UBNeuro, Dept Med,Barcelona Clin Schizophrenia Unit,FCRB,ID, Barcelona, Spain - Author
Univ Barcelona, CIBERSAM ISCIII, Hosp Clin,Dept Med,Fac Med & Ciencies Salut,FCRB,I, Inst Neurosci UB Neuro,Bipolar & Depress Disorders, Barcelona 08036, Catalonia, Spain - Author
Univ Cadiz, Hosp Univ Jerez de la Frontera, Cadiz, Spain - Author
Univ Perugia, Dept Psychiat, Perugia, Italy - Author
Univ Rovira i Virgili, Hosp Univ Inst Pere Mata, Inst Invest Sanitaria Pere Virgili IISPV, CIBERSAM ISCIII, Reus, Tarragona, Spain - Author
Vall dHebron Res Inst VHIR, Psychiat Genet Unit, CIBERSAM ISCIII, Barcelona, Catalonia, Spain - Author
See more

Abstract

Objective: This study was aimed at identifying sex differences in patients presenting a first episode mania (FEM) or psychosis (FEP) to help shaping early treatment strategies focused on sex differences. Methods: Patients with a FEM or FEP underwent a clinical, neuropsychological (neurocognitive functions and emotional intelligence) and functional assessment. Performance on those variables was compared between groups through general linear model, with sex and group (FEM vs FEP) as main effects and group by sex interactions. Results: The total sample included 113 patients: FEM = 72 (45.83 % females) and FEP = 41 (46.34 % females). There were significant main effects for group (not for sex) for most of the clinical features (depressive, negative and positive symptoms) and psychosocial functioning (chi(2) = 8.815, p = 0.003). As for neuropsychological performance, there were significant main effects for sex and group. Females performed better than males in verbal memory (chi(2) = 9.038, p = 0.003) and obtained a higher emotional intelligence quotient (chi(2) = 13.20, p < 0.001). On the contrary, males obtained better results in working memory (chi(2) = 7.627, p = 0.006). FEP patients significantly underperformed FEM patients in most cognitive domains. There were significant group by sex interactions for few neuropsychological variables, namely processing speed (chi(2 )= 4.559, p = 0.033) and verbal fluency (chi(2) = 8.913, p = 0.003).
[+]

Keywords

1st-episode schizophreniaAdultAlcohol consumptionArticleBipolar disorderCannabis useClinical assessmentClinical featureCognitive impairmentCohort analysisComparative studyControlled studyCreativityCross-sectional studyDemographicsDepressionEarly psychosisEmotional intelligenceEnergyExecutive functionFemaleFirst episode maniaFirst episode psychosisFunctional assessmentGender-differencesHumanHumansIntelligence quotientMajor clinical studyMaleManiaMemoryMetaanalysisMontgomery asberg depression rating scaleNeuropsychological testsPerformancPositive and negative syndrome scaleProcessing speedProdromal symptomProdromal symptomsProdromesPsychosisPsychotic disordersRetrospective studyScaleSelf esteemSemi structured interviewSex differenceSex differencesSex factorsSleepSocial cognitionSocial psychologySociodemographicsSpeechStructured clinical interview for dsm disordersSymptomsVerbal memoryVisual memoryWechsler adult intelligence scaleWorking memoryYoung adultYoung mania rating scale

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal JOURNAL OF AFFECTIVE DISORDERS due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2025, it was in position 33/288, thus managing to position itself as a Q1 (Primer Cuartil), in the category Psychiatry.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-05:

  • WoS: 3
  • Europe PMC: 3
[+]

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 35.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 35 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).
[+]

Leadership analysis of institutional authors

This work has been carried out with international collaboration, specifically with researchers from: Italy; Peru.

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (Verdolini, Norma).

the author responsible for correspondence tasks has been Vieta Pascual, Eduard.

[+]