{rfName}
Th

Indexed in

Citations

518

Altmetrics

Analysis of institutional authors

Juan, MeAuthorPlanas, JmCorresponding Author

Share

March 5, 2025
Publications
>
Article
No

The daily oral administration, of high doses of trans-resveratrol to rats for 28 days is not harmful

Publicated to: Journal Of Nutrition. 132 (2): 257-260 - 2002-02-01 132(2), DOI: 10.1093/jn/132.2.257

Authors:

Juan, ME; Vinardell, MP; Planas, JM
[+]

Affiliations

- Author

Abstract

trans-3,5,4'-Trihydroxystilbene (trans-resveratrol) is a phytochemical present in peanuts, grapes and wine with beneficial effects such as protection against cardiovascular disease and cancer prevention. The purpose of this! study was to evaluate whether high doses of trans-resveratrol; have harmful effects on Sprague-Dawley rats. trans-Resveratrol was administered orally to male rats for 28 d at a dose of 20 mg/(kg (.) d), 1000 times the amount consumed by a 70-kg person taking 1.4 g of trans-resveratrol/d. Body weight, and food and water consumption did not differ between rats: treated with trans-resveratrol and the control group. Hematologic and biochemical variables were not affected by, the treatment. Histopathologic examination of the organs obtained at autopsy did not reveal any alterations. These results support the view that repeated consumption of trans-resveratrol at 20 mg/(kg (.) d) does not adversely affect the variables tested in rats.
[+]

Keywords

alcoholhplcldl oxidationphytochemicalspolyphenolsquercetinratsred wineAlcoholFunctional foodsHplHplcLdl oxidationPhytochemicalsPolyphenolsQuercetinRatRatsRed wineTrans-resveratrol

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal JOURNAL OF NUTRITION due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2002, it was in position 4/50, thus managing to position itself as a Q1 (Primer Cuartil), in the category Nutrition & Dietetics.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-03:

  • WoS: 244
[+]

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-03:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 129.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 129 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.
  • The number of mentions on the social network Facebook: 2 (Altmetric).
[+]

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Juan Olivé, Emília) and Last Author (Planas Rosselló, Joana M).

the author responsible for correspondence tasks has been Planas Rosselló, Joana M.

[+]