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Analysis of institutional authors

Sandoval-Clavijo AAuthorAlos LAuthorCarrera CAuthorMalvehy JAuthorPuig SAuthorToll AAuthorPodlipnik SCorresponding Author

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Prognostic role of microsatellites in melanoma and implications in the AJCC classification system: a cohort study

Publicated to:Journal Of The American Academy Of Dermatology. 88 (2): 338-347 - 2023-11-01 88(2), DOI: 10.1016/j.jaad.2022.10.027

Authors: Riquelme-Mc Loughlin, Constanza; Sandoval-Clavijo, Alejandra; de Tord, Maria Blanco; Boada, Aram; Alos, Llucia; Garcia, Adriana; Carrera, Cristina; Malvehy, Josep; Puig, Susana; Toll, Agusti; Podlipnik, Sebastian

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Abstract

There is limited information on microsatellite survival outcomes in melanoma patients.To evaluate survival outcomes in patients with microsatellites, assess their role within stage III stratification of the AJCC classification. Assess the results of sentinel lymph node biopsies (SLNB) in patients with microsatellites.A retrospective bicenter cohort study from 1998 to 2019 including patients diagnosed with invasive cutaneous melanoma.Of a total of 5216 patients, 108 (2.1%) had microsatellites at initial staging. Survival analysis showed that microsatellites were an independent risk factor with decreased overall survival (OS), melanoma specific survival (MSS) and disease-free survival (DSF) with hazard ratios (HR) of 1.57, 1.76 and 1.76 respectively. Stratified analysis in stage III patients showed a 5-year OS of stage IIIB patients with microsatellites of 35% (95% CI 17.3-73.4%) and MSS of 45% (95% CI 23.1-87.5).A retrospective study.Microsatellites were associated with other adverse melanoma prognostic factors. A multivariate Cox regression analysis showed that it is an independent risk factor for worse OS, MSS and DFS. Stage IIIB patients with microsatellites had a worse OS and MSS whereas stage IIIC patients had worse OS but not MSS.Copyright © 2022. Published by Elsevier Inc.

Keywords

Clinical decision makingClinical decision-makingCohort studiesHumansMelanomaMelanoma, cutaneous malignantMicrosatellite repeatsMicrosatellitesNeoplasm stagingPrognosisRetrospective studiesSentinel lymph node biopsySkin neoplasmsStaging

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Journal Of The American Academy Of Dermatology due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2023, it was in position 1/94, thus managing to position itself as a Q1 (Primer Cuartil), in the category Dermatology. Notably, the journal is positioned above the 90th percentile.

From a relative perspective, and based on the normalized impact indicator calculated from World Citations provided by WoS (ESI, Clarivate), it yields a value for the citation normalization relative to the expected citation rate of: 1.68. This indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: ESI Nov 14, 2024)

This information is reinforced by other indicators of the same type, which, although dynamic over time and dependent on the set of average global citations at the time of their calculation, consistently position the work at some point among the top 50% most cited in its field:

  • Field Citation Ratio (FCR) from Dimensions: 2.26 (source consulted: Dimensions Jun 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-06-04, the following number of citations:

  • WoS: 5
  • Scopus: 6
  • Europe PMC: 1
  • OpenCitations: 4

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-06-04:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 7.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 7 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 10.
  • The number of mentions on the social network X (formerly Twitter): 6 (Altmetric).

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: Last Author (Podlipnik, Sebastian).

the author responsible for correspondence tasks has been Podlipnik, Sebastian.