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Analysis of institutional authors

Cervera Guadix, RemediosAuthorGrau Corral, InmaculadaAuthorCervera, RCorresponding AuthorRamos-Casals, MAuthorSiso, AAuthorRamirez, FAuthorVives, JAuthor

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September 24, 2024
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Anti-chromatin antibodies in systemic lupus erythematosus:: a useful marker for lupus nephropathy

Publicated to:Annals Of The Rheumatic Diseases. 62 (5): 431-434 - 2003-05-01 62(5), DOI: 10.1136/ard.62.5.431

Authors: Cervera, R; Viñas, O; Ramos-Casals, M; Font, J; García-Carrasco, M; Sisó, A; Ramírez, F; Machuca, Y; Vives, J; Ingelmo, M; Burlingame, RW

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Abstract

Background: Anti-chromatin antibodies have recently been described in patients with systemic lupus erythematosus (SLE) and it has been suggested that their presence is associated with lupus nephritis. Objective: To assess the prevalence and clinical associations of these antibodies in SLE. Methods: The presence of anti-chromatin antibodies in 100 patients with SLE was investigated by an enzyme linked immunosorbent assay (ELISA). To determine the specificity of these antibodies, 100 patients with primary Sjogren's syndrome, 30 with primary antiphospholipid syndrome (APS), 10 with systemic sclerosis, and 100 normal controls were also tested. Results: Positive levels were detected in 69/100 (69%) patients with SLE. In contrast, they were found in only 8/100 (8%) of those with primary Sjogren's syndrome, in 1/10 (10%) with systemic sclerosis, in 2/30 (7%) with primary APS, and in none of the 100 healthy controls. Patients with anti-chromatin antibodies had a twofold higher prevalence of lupus nephropathy than those without these antibodies (58% v 29%, p

Keywords

AdolescentAdultAgedAnalysisAntibodies, antinuclearAntibody specificityAnticardiolipin antibodiesAntinucleosome antibodiesAntiphospholipid syndromeAutoantibodiesAutoantigensBiomarkersChildChromatinClassificationDnaEnzyme-linked immunosorbent assayFemaleHumansIsotype distributionLupus erythematosus, systemicLupus nephritisMaleMiddle agedNucleosomesProspective studiesRevised criteriaSclerodermScleroderma, systemicSjögren's syndrome

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Annals Of The Rheumatic Diseases due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2003, it was in position 3/21, thus managing to position itself as a Q1 (Primer Cuartil), in the category Rheumatology.

From a relative perspective, and based on the normalized impact indicator calculated from the Field Citation Ratio (FCR) of the Dimensions source, it yields a value of: 15.9, which indicates that, compared to works in the same discipline and in the same year of publication, it ranks as a work cited above average. (source consulted: Dimensions Jul 2025)

Specifically, and according to different indexing agencies, this work has accumulated citations as of 2025-07-26, the following number of citations:

  • WoS: 80
  • Scopus: 91
  • Europe PMC: 60
  • Google Scholar: 150

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-07-26:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 66.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 70 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 1.1.
  • The number of mentions on the social network X (formerly Twitter): 2 (Altmetric).

Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Cervera Segura, Ricard) .

the author responsible for correspondence tasks has been Cervera Segura, Ricard.