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Analysis of institutional authors

Cuervo, GuillermoCorresponding Author

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October 15, 2024
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Effect of a bundle intervention on adherence to quality-of-care indicators and on clinical outcomes in patients with Staphylococcus aureus bacteraemia hospitalized in non-referral community hospitals

Publicated to: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 79 (11): 2858-2866 - 2024-08-30 79(11), DOI: 10.1093/jac/dkae298

Authors:

Escrihuela-Vidal, F; Chico, C; González, BB; Sánchez, DV; Lerida, A; Escudero, ED; Sanmarti, M; Gonzalez, LL; Simonetti, AF; Conde, AC; Muelas-Fernandez, M; Diaz-Brito, V; Quintana, SGH; Oriol, I; Berbel, D; Camara, J; Grillo, S; Pujol, M; Cuervo, G; Carratala, J
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Affiliations

Bellvitge Univ Hosp, Dept Infect Dis, IDIBELL, Barcelona, Spain - Author
Bellvitge Univ Hosp, Dept Microbiol, IDIBELL, Barcelona, Spain - Author
Complex Hosp Univ Moises Broggi, Dept Internal Med, Sant Joan Despi, Barcelona, Spain - Author
Hosp Comarcal Alt Penedes, Dept Internal Med, Vilafranca Del Penedes, Barcelona, Spain - Author
Hosp Residencia St Camil, Dept Internal Med, Barcelona, Spain - Author
Hosp Santa Creu i St Pau, Infect Dis Unit, Barcelona, Spain - Author
Hosp Viladecans, Inst Catala Salut Area Metropolitana Sud, Dept Internal Med, Viladecans, Barcelona, Spain - Author
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Infecciosas CIB, Madrid, Spain - Author
Inst Salud Carlos III, Ctr Invest Biomed Red Enfermedades Respiratorias C, Madrid, Spain - Author
Parc Sanit St Joan Deu, Dept Infect Dis, Barcelona, Spain - Author
Univ Barcelona, Hosp Clin, Infect Dis Serv, IDIBAPS, Barcelona, Spain - Author
Univ Barcelona, Sch Med & Hlth Sci, Dept Clin Sci, Barcelona, Spain - Author
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Abstract

Background Although a significant number of cases of Staphylococcus aureus bacteraemia (SAB) are managed at non-referral community hospitals, the impact of a bundle-of-care intervention in this setting has not yet been explored.Methods We performed a quasi-experimental before-after study with the implementation of a bundle of care for the management of SAB at five non-referral community hospitals and a tertiary care university hospital. Structured recommendations for the five indicators selected to assess quality of care were provided to investigators before the implementation of the bundle and monthly thereafter. Primary endpoints were adherence to the bundle intervention and treatment failure, defined as death or relapse at 90 days of follow-up.Results One hundred and seventy patients were included in the pre-intervention period and 103 in the intervention period. Patient characteristics were similar in both periods. Multivariate analysis controlling for potential confounders showed that performance of echocardiography was the only factor associated with improved adherence to the bundle in the intervention period (adjusted OR 2.13; 95% CI 1.13-4.02). Adherence to the bundle, performance of follow-up blood cultures, and adequate duration of antibiotic therapy for complicated SAB presented non-significant improvements. The intervention was not associated with a lower rate of 90 day treatment failure (OR 1.11; 95% CI 0.70-1.77).Conclusions A bundle-of-care intervention for the management of SAB at non-referral community hospitals increased adherence to quality indicators, but did not significantly reduce rates of 90 day mortality or relapse.
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Keywords

AdultAgedAged, 80 and overAnti-bacterial agentsAntibiotic agentAntibiotic sensitivityAntibiotic therapyAntiinfective agentArticleAvaluació de resultats (assistència mèdica)BacteremiaBacterium isolateBlood cultureBlood-stream infectionsCare bundleCefazolinClinical outcomeCloxacillinCohort analysisCommunity hospitalConsultationCorticosteroidDaptomycinDementiaDrug therapyEchocardiographyEndocarditisExperienceFemaleFollow upGuideline adherenceHealth care qualityHospital patientHospitals, communityHumanHumansImmunosuppressive agentImpactIntervention studyLinezolidMajor clinical studyMaleManagementMethicillin resistanceMethicillin resistant staphylococcus aureus bacteremiaMethicillin susceptible staphylococcus aureus bacteremiaMeticillinMicrobiologíaMicrobiologyMiddle agedMinimum inhibitory concentrationMortalityMulticenter studyOutcome assessment (medical care)Patient care bundlesPneumoniaPolypeptide antibiotic agentProceduresProtocol complianceQuality indicators, health careQuality of health careQuasi experimental studyStaphylococcal infectionsStaphylococcus aureusStaphylococcus aureus bacteremiaStaphylococcus infectionTertiary health careTransesophageal echocardiographyTransthoracic echocardiographyTreatment durationTreatment failureTreatment outcomeUniversity hospitalVancomycinVery elderly

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY due to its progression and the good impact it has achieved in recent years, according to the agency Scopus (SJR), it has become a reference in its field. In the year of publication of the work, 2024 there are still no calculated indicators, but in 2023, it was in position , thus managing to position itself as a Q1 (Primer Cuartil), in the category Infectious Diseases.

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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-04:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 8.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 7 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 4.
  • The number of mentions on the social network X (formerly Twitter): 8 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

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Leadership analysis of institutional authors

the author responsible for correspondence tasks has been Cuervo Requena, Guillermo.

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Awards linked to the item

The PROMISE study was funded by a research grant of Institut d'Investigacio Biomedica de Bellvitge (IDIBELL) (PR008/21). F.E.V. received a personal research grant from Institut d'Investigacio Biomedica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Spain, during 2021-22. The funding agencies had no involvement in the preparation of the manuscript.
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