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Analysis of institutional authors

Barroso S.AuthorGarrabou G.Author
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The effects of HIV and the antiretrovirals on the mitochondria

Publicated to:Mitochondrial Intoxication. 351-378 - 2022-01-01 (), DOI: 10.1016/B978-0-323-88462-4.00031-6

Authors: Barroso S; Garrabou G

Affiliations

Muscle Research and Mitochondrial Function Laboratory; Cellex-IDIBAPS; Faculty of Medicine and Health Sciences; University of Barcelona; Barcelona; Spain - Author

Abstract

Among different mitochondrial toxic agents, the human immunodeficiency virus (HIV) has been proposed as a mitochondrial aggressor that induces cellular damage through mitohormesis disturbances. Antiretroviral treatment associated to HIV reduces morbimortality related to the natural history of the infection. However, it also contributes to the mitochondrial toxicity that, added to the mitochondrial toxic effects of the basal infection, leads to adverse clinical secondary effects. Fortunately, new antiretroviral families and drugs with lesser mitochondrial toxic profiles are being developed to decrease these secondary effects. Thus, increasing treatment safety and adherence, while maintaining efficacy. The present chapter of this book explains the different contribution to the mitochondrial toxic profile produced either by the virus or by the antiretroviral treatment. © 2023 Elsevier Inc. All rights reserved.

Keywords
AntiretroviralFusion inhibitorsHaartHivInstisMitotoxicityNnrtisNrtiProtease inhibitors

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

Esta aportación ha sido publicada por la editorial Elsevier according to the SPI Ranking, it has become a reference in its field. In the year of publication of the work, 2022-01-01, es considerada como de las mejores posicionadas, concretamente el Q1.

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2025-04-30:

  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 9 (PlumX).
Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Barroso Rodriguez, Sergio) and Last Author (Garrabou Tornos, Glòria).